This project is based on a pilot with the FDA and will create a cloud-based data use agreement toolkit to support the entry of de-identified EHR data from partner institutions into the sandboxes. The project will leverage a preconfigured FHIR repository maintained on the CD2H/NCATS cloud or behind the partner institution’s firewall as a demonstration. The team will work with the community to write Governance, SOPs, and policy for CTSA informatics community collaboration. A pan-sandbox Governance group will have CD2H and community representatives to contribute subject matter for specific domains.