CD2H: Harmonizing the Informatics Community

CD2H: Harmonizing the Informatics Community

The National COVID Cohort Collaborative (N3C)

N3C Logo

By leveraging our collective data resources, unparalleled analytics expertise, and medical insights from expert clinicians, we can synergize discoveries that address this pandemic beyond the sum of our parts. The National COVID Cohort Collaborative (N3C) is a collaboration among the NCATS-supported Clinical and Translational Science Awards (CTSA) Program hubs, the National Center for Data to Health (CD2H), distributed clinical data networks (PCORnet, OHDSI, ACT/i2b2, TriNetX), and other partner organizations, with overall stewardship by NIH’s National Center for Advancing Translational Sciences (NCATS). The N3C aims to improve the efficiency and accessibility of analyses using a large row-level (patient-level) COVID-19 clinical dataset and demonstrate a novel approach for collaborative pandemic sharing.

CD2H advances translational research to improve patient care

The National Center for Data to Health (CD2H) accelerates advancements in informatics by using findable, accessible, interoperable, and reusable (FAIR) principles to promote collaboration across the Clinical and Translational Science Awards (CTSA) Program community. CD2H tools and resources make it simple and valuable for CTSA Program members to get engaged, connect with peers, and contribute. By promoting collaboration, CD2H fosters a robust translational science informatics ecosystem that collectively develops solutions to solve clinical problems faster, more efficiently, and more effectively. CTSA Program members are poised to lead this charge by harnessing collective expertise and strengths to solve key informatics challenges. With this team science approach, advancements in translational research can ultimately improve patient care. 

Featured Informatics Expert

Lauren Gardner Headshot
Lauren Gardner, PhD
Body Summary (Front Page)
Associate professor at Johns Hopkins Whiting School of Engineering and creator of the JHU COVID-19 Dashboard.

News

National Library of Medicine (NLM) is preparing to launch a pilot project to test the viability of making preprints resulting from NIH-funded research available via PubMed Central (PMC).
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NCATS is an integrator, bringing together diverse people, technologies, and information to produce insights and advances that no one could do alone.
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Scientists creating secure, central database of electronic health records from coronavirus patients
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The COVID-19 host genetics initiative brings together the human genetics community to generate, share, and analyze data to learn the genetic determinants of COVID-19 susceptibility, severity, and outcomes.
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We can find effective treatments for COVID-19 much faster by sharing protocols for randomized clinical trials. This platform is a home for RCT protocols that are available for collaboration.
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Due to the emergent need for better understanding of COVID-19 and the development of patient-specific clinical risk scores and early warning tools, CD2H has developed a platform to support analytic and machine learning hypotheses on clinical data.
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“Scientists are a tremendous resource for this country, and it’s not something that should just be confined to the coasts,” Michael Wells said. “It’s something that everyone should be able to benefit from.”
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Real-time study will conduct targeted statewide COVID-19 testing, precision mapping to help safely ease physical distancing, control future outbreaks
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CD2H has developed a platform to support testing analytic and machine learning hypotheses on clinical data, without data sharing, as a platform to rapidly discover and implement approaches for care.
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The COVID-19 Consumer Data Protection Act would provide all Americans with more transparency, choice, and control over the collection and use of their personal health, geolocation, and proximity data.
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Cloud-based N3C will accept data via multiple data models and transform them into a common analytic model for research
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Be part of the National Library of Medicine (NLM) future.
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Epic dropping opposition to a federal rule designed to improve patients’ access to their medical records, removing a potential barrier to its implementation.
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NCATS recently issued two Notices of Special Interest that highlight the urgent need for research on the 2019 novel coronavirus (SARS-CoV-2) and the disease it causes, 2019 novel Coronavirus Disease (COVID-19).
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AMIA is committed to providing guidance and updates on COVID-19 for the informatics community with data resources, weekly webinars, and literature publications.
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Interested in a career at the nation’s primary resource for diverse biomedical literature, data, and information, and with the world’s largest biomedical research library? Applications due by April 30, 2020 11:59 pm ET.
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In collaboration with several NIH institutes and distributed clinical data networks, CD2H has created the National COVID Cohort Collaborative (N3C), a centralized, secure, limited access portal to access COVID-19 clinical data.
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REDCap has found widespread use in the public health response to the COVID-19 pandemic.
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Your input is vital to ensuring that the NIH-Wide Strategic Plan for Fiscal Years 2021–2025 sets forth biomedical research on a promising and visionary path.
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The nation's artificial intelligence experts are to develop new text and data mining techniques that can help the science community answer high-priority scientific questions related to COVID-19.
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NIH’s Office of Data Science Strategy (ODSS) has one- to two-year positions open in the Data and Technology Advancement (DATA) National Service Scholar Program.
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The Office of the National Coordinator (ONC) for Health Information Technology has published the final rule intended to move the health care ecosystem in the direction of interoperability to improve quality and accessibility of information.
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The Patient-Centered Outcomes Research Institute is hiring for a Program Officer (senior roles available) for Evaluation & Analysis.
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This RFI invites feedback on the scope of its programs and possible future directions to maximize the benefits of those programs.
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The U.S. Department of Health and Human Services (HHS) released the draft 2020-2025 Federal Health IT Strategic Plan for public comment.
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We are very pleased to announce the winner of the 2019 Idea Competition: University of Alabama, Birmingham “Automated Scoring of Radiographic Damage in Rheumatoid Arthritis” (PI S. Louis Bridges).
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The National Institutes of Health’s Office of Data Science Strategy will host a virtual workshop on assessing dataset and data resource value and reach.
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The CLIC Virtual Tour is designed to give everyone involved with the CTSA Program, regardless of in what capacity, an overview of what CLIC provides and how to make it work for you.
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The Office of Data Science Strategy at the National Institutes of Health and the National Library of Medicine are hosting a workshop (link is external) on the Role of Generalist Repositories to Enhance Data Discoverability and Reuse on Feb. 11-12.
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The White House Office of Science and Technology Policy is seeking public comments on a draft set of desirable characteristics of data repositories used to locate, manage, share, and use data resulting from Federally funded research.
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CD2H is seeking community project proposals for which we can offer development support, help initialize and support larger funding proposals, or otherwise consult with CTSA hubs on their collaborative informatics efforts.
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This Show and Tell will feature DREAM Challenges and highlight how the CD2H is bringing this successful model to the CTSA Community.
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CD2H Dec 2018 Newsletter Now Available
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CD2H Oct 2018 Newsletter Now Available
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CD2H Sep 2018 Newsletter Now Available
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CD2H Aug 2018 Newsletter Now Available
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Learn more about the CD2H’s approach to accelerating informatics innovation
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Sign up now for the CD2H monthly newsletter
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CD2H announcement from NIH/NCATS
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The CTSA Program Data to Health Coordinating Center is delighted to announce the release of the CD2H website!
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Events

Jun 01
12:00 am - 12:00 am
Jun 03
8:00 am - 11:00 am
Jun 03
10:00 am - 11:00 am
Jun 04
10:00 am - 11:00 am
Jun 05
10:00 am - 11:00 am
Jun 09
12:00 pm - 1:00 pm

CD2H Community Cores

Resource Discovery

This core aims to create and enhance tools and information resources that empower the CTSA hubs to find and share them more easily.

Informatics Maturity & Best Practices

This core aims to determine, define, and disseminate best practices in data use and informatics to the CTSA community.

Next Generation Data Sharing

This core aims to develop an open-science ethos and unite CTSA community data sharing with broader global efforts.

Tools & Cloud Infrastructure

This core aims to establish a common tool and cloud computing architecture to provide CTSA hubs with an affordable, easy to use, and scalable deployment paradigm.

11

Current CTSA Projects

98

Institutions working with CD2H

220

Faculty working with CD2H

NCATS Translational Science Spectrum

Public Health In this stage, researchers study health outcomes at the population level to determine the effects of diseases and identify efforts to prevent, diagnose, and treat them. Clinical Implementation This stage involves the adoption of interventions that have been demonstrated to be useful in a research environment into routine clinical care for the general population. Clinical Research Research in this stage includes studies to better understand a disease in humans and relate this knowledge to findings in cell or animal models; testing and refinement of new technologies in people; testing of interventions for safety and effectiveness in those with or without disease; and outcomes of health services research. Preclinical Research Preclinical research connects the basic science of disease with human medicine. During this stage, scientists develop model interventions to further understand the basis of a disease or disorder and find ways to treat it. Basic Research Basic research involves scientific exploration that can reveal fundamental mechanisms of biology, disease, or behavior. Every stage of the translational research spectrum builds upon and informs basic research. Translational Science The field of investigation focused on understanding the scientific and operational principles underlying each step of the translational process. TS Spectrum The translational science spectrum represents each stage of research along the path from the biological basis of health and disease to interventions that improve the health of individuals and the public. "> "> "> "> "> "> "> "> Learn more