CD2H: Harmonizing the Informatics Community

CD2H: Harmonizing the Informatics Community

The National COVID Cohort Collaborative (N3C)

N3C Logo

By leveraging our collective data resources, unparalleled analytics expertise, and medical insights from expert clinicians, we can synergize discoveries that address this pandemic beyond the sum of our parts. The National COVID Cohort Collaborative (N3C) is a complementary and synergistic partnership among the Clinical and Translational Science Awards (CTSA) Program hubs, the National Center for Data to Health (CD2H, distributed clinical data networks (PCORnet, OHDSI, ACT, TriNetX), and other partner organizations, with overall stewardship by NIH’s National Center for Advancing Translational Sciences. The N3C aims to improve the efficiency and accessibility of analyses using a very large row-level (patient-level) COVID-19 clinical dataset and demonstrate a novel approach for collaborative pandemic data sharing.

CD2H advances translational research to improve patient care

The National Center for Data to Health (CD2H) accelerates advancements in informatics by using findable, accessible, interoperable, and reusable (FAIR) principles to promote collaboration across the Clinical and Translational Science Awards (CTSA) Program community. CD2H tools and resources make it simple and valuable for CTSA Program members to get engaged, connect with peers, and contribute. By promoting collaboration, CD2H fosters a robust translational science informatics ecosystem that collectively develops solutions to solve clinical problems faster, more efficiently, and more effectively. CTSA Program members are poised to lead this charge by harnessing collective expertise and strengths to solve key informatics challenges. With this team science approach, advancements in translational research can ultimately improve patient care. 

Featured Informatics Expert

Charisse Madlock-Brown
Charisse Madlock-Brown, PhD, MLS
Body Summary (Front Page)
Assistant Professor of Health Informatics and Information Management and leader of the UTHSC Research Pipelines labs.

News

Hacktoberfest Contributor's Guide: How To Find and Contribute to Open-Source Projects
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The goal of the N3C is to systematically collect, harmonize, and make available patient data from healthcare providers nationwide to accelerate advances in COVID-19 clinical care.
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The old version of the registration/onboarding form has officially been deprecated and now replaced with this new form. Become a member now to engage with CD2H!
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Free webinar to examine the importance of biobanking in precision medicine, from early-stage research to diagnostics and treatments.
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The aim is to produce a standard machine-readable format that will be based on existing ontologies. Please RSVP to fjeanson@yahoo.com to be invited to the first bi-weekly meeting of this group.
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Innovative advances in medical products and transparency in the clinical trials process depend on compliance with ClinicalTrials.gov submission requirements.
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Don't miss this virtual event from Government CIO Media & Research! Thursday August 13th 8:00 am PT/11:00 am ET.
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The overarching goal is to understand factors that have led to disproportionate burden of the pandemic on these underserved populations so that interventions can be implemented to decrease these disparities.
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The USCDI will facilitate the use of clinical data in research studies and enable greater consistency in clinical research data that are shared.
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Philip R.O. Payne, PhD, director of the Institute for Informatics at Washington University School of Medicine in St. Louis, has been named associate dean for health information and data science, and chief data scientist for the School of Medicine.
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N3C leaders Melissa Haendel, PhD and Chris Chute, MD, DrPH along with Andrew Chan, MD and Stephen Hewitt, MD talk about Big Data and Collaboration to fight COVID-19. Read the article!
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Notice of Special Interest (NOSI) NOT-TR-20-011 is ongoing through July 10, 2021 - Apply for funding today to advance the translation of research findings into diagnostics, therapeutics, and vaccines!
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Listen to a recording from NIH Director Dr. Francis Collins & NIAID Director Dr. Anthony Fauci for the latest information on the status of COVID-19.
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Investigators are encouraged to submit clear and detailed descriptions of their novel COVID-19 methodological results. Submissions for the November issue of the Journal of Biomedical Informatics are due by October 15, 2020.
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10 New LOINC Codes - Updated 06-26-2020
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Scripps Research joins national effort to develop medical record analytics to improve COVID-19 patient outcomes
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The Call for Participation for the AMIA 2021 Informatics Summit is heating up! AMIA is looking for submissions describing the latest innovations you are creating in Bioinformatics, CRI, Informatics Implementation, & Data Science. Submissions due August 13
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For a themed issue on the Design, Development, Evaluation, and Dissemination of Team Science Interventions.
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“This effort aims to transform clinical information into knowledge urgently needed to study COVID-19, including health risk factors that indicate better or worse outcomes of the disease, and identify potentially effective treatments,”
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Assuring a rapid and thorough public health response to the COVID-19 pandemic necessitates complete and comprehensive laboratory testing data.
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The National Institutes of Health has launched a centralized, secure enclave to store and study vast amounts of medical record data from people diagnosed with coronavirus disease across the country.
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NCATS is seeking creative approaches to raising awareness about Rare Diseases. Deadline extended; submit your entry by 6/15/2020.
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The NIH Preprint Pilot, a project of NIH’s National Library of Medicine (NLM), is intended to increase early discoverability of NIH-supported research results, maximizing the possible impact of the research.
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Given the rapid spread of COVID-19, the need to accurately document new cases of the coronavirus, and analyze and share patient data, is critical to patients, their communities, and the healthcare professionals who serve them.
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Join Dr. Afshin Beheshti and the COV-IRT team for their 2nd Annual Virtual Symposium July 17, 2020 8 am PT/10 am CT/11 am ET. Speakers and meeting link to be announced.
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View ONC's Cures Act Final Rule timeline to help you stay on track as you work to adopt new technologies to meet these regulations.
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The Journal of Clinical and Translational Science recently announced a call for submissions for a special themed issue focused on the Design, Development, Evaluation, and Dissemination of Team Science Interventions in Clinical and Translational Research.
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The FDA published a new set of validation data from five additional coronavirus antibody tests, including diagnostics that have received federal authorizations and some that have since been removed from public sale.
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The COVID-19 research database enables public health and policy researchers to use real-world data to better understand and combat the COVID-19 pandemic.
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The Lancet, one of the world’s top medical journals, retracted an influential study that raised alarms about the safety of the experimental Covid-19 treatments chloroquine and hydroxychloroquine amid scrutiny of the data underlying the paper.
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National Library of Medicine (NLM) is preparing to launch a pilot project to test the viability of making preprints resulting from NIH-funded research available via PubMed Central (PMC).
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NCATS is an integrator, bringing together diverse people, technologies, and information to produce insights and advances that no one could do alone.
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Scientists creating secure, central database of electronic health records from coronavirus patients
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The COVID-19 host genetics initiative brings together the human genetics community to generate, share, and analyze data to learn the genetic determinants of COVID-19 susceptibility, severity, and outcomes.
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We can find effective treatments for COVID-19 much faster by sharing protocols for randomized clinical trials. This platform is a home for RCT protocols that are available for collaboration.
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Due to the emergent need for better understanding of COVID-19 and the development of patient-specific clinical risk scores and early warning tools, CD2H has developed a platform to support analytic and machine learning hypotheses on clinical data.
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“Scientists are a tremendous resource for this country, and it’s not something that should just be confined to the coasts,” Michael Wells said. “It’s something that everyone should be able to benefit from.”
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Real-time study will conduct targeted statewide COVID-19 testing, precision mapping to help safely ease physical distancing, control future outbreaks
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The COVID-19 Consumer Data Protection Act would provide all Americans with more transparency, choice, and control over the collection and use of their personal health, geolocation, and proximity data.
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CD2H has developed a platform to support testing analytic and machine learning hypotheses on clinical data, without data sharing, as a platform to rapidly discover and implement approaches for care.
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Cloud-based N3C will accept data via multiple data models and transform them into a common analytic model for research
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Be part of the National Library of Medicine (NLM) future.
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Epic dropping opposition to a federal rule designed to improve patients’ access to their medical records, removing a potential barrier to its implementation.
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NCATS recently issued two Notices of Special Interest that highlight the urgent need for research on the 2019 novel coronavirus (SARS-CoV-2) and the disease it causes, 2019 novel Coronavirus Disease (COVID-19).
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AMIA is committed to providing guidance and updates on COVID-19 for the informatics community with data resources, weekly webinars, and literature publications.
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Interested in a career at the nation’s primary resource for diverse biomedical literature, data, and information, and with the world’s largest biomedical research library? Applications due by April 30, 2020 11:59 pm ET.
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In collaboration with several NIH institutes and distributed clinical data networks, CD2H has created the National COVID Cohort Collaborative (N3C), a centralized, secure, limited access portal to access COVID-19 clinical data.
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REDCap has found widespread use in the public health response to the COVID-19 pandemic.
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The nation's artificial intelligence experts are to develop new text and data mining techniques that can help the science community answer high-priority scientific questions related to COVID-19.
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Your input is vital to ensuring that the NIH-Wide Strategic Plan for Fiscal Years 2021–2025 sets forth biomedical research on a promising and visionary path.
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NIH’s Office of Data Science Strategy (ODSS) has one- to two-year positions open in the Data and Technology Advancement (DATA) National Service Scholar Program.
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The Office of the National Coordinator (ONC) for Health Information Technology has published the final rule intended to move the health care ecosystem in the direction of interoperability to improve quality and accessibility of information.
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The Patient-Centered Outcomes Research Institute is hiring for a Program Officer (senior roles available) for Evaluation & Analysis.
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This RFI invites feedback on the scope of its programs and possible future directions to maximize the benefits of those programs.
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We are very pleased to announce the winner of the 2019 Idea Competition: University of Alabama, Birmingham “Automated Scoring of Radiographic Damage in Rheumatoid Arthritis” (PI S. Louis Bridges).
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The White House Office of Science and Technology Policy is seeking public comments on a draft set of desirable characteristics of data repositories used to locate, manage, share, and use data resulting from Federally funded research.
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The Office of Data Science Strategy at the National Institutes of Health and the National Library of Medicine are hosting a workshop (link is external) on the Role of Generalist Repositories to Enhance Data Discoverability and Reuse on Feb. 11-12.
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The CLIC Virtual Tour is designed to give everyone involved with the CTSA Program, regardless of in what capacity, an overview of what CLIC provides and how to make it work for you.
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The National Institutes of Health’s Office of Data Science Strategy will host a virtual workshop on assessing dataset and data resource value and reach.
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The U.S. Department of Health and Human Services (HHS) released the draft 2020-2025 Federal Health IT Strategic Plan for public comment.
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CD2H is seeking community project proposals for which we can offer development support, help initialize and support larger funding proposals, or otherwise consult with CTSA hubs on their collaborative informatics efforts.
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This Show and Tell will feature DREAM Challenges and highlight how the CD2H is bringing this successful model to the CTSA Community.
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CD2H Dec 2018 Newsletter Now Available
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CD2H Oct 2018 Newsletter Now Available
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CD2H Sep 2018 Newsletter Now Available
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CD2H Aug 2018 Newsletter Now Available
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Learn more about the CD2H’s approach to accelerating informatics innovation
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Sign up now for the CD2H monthly newsletter
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CD2H announcement from NIH/NCATS
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The CTSA Program Data to Health Coordinating Center is delighted to announce the release of the CD2H website!
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Events

CD2H Community Cores

Resource Discovery

This core aims to create and enhance tools and information resources that empower the CTSA hubs to find and share them more easily.

Informatics Maturity & Best Practices

This core aims to determine, define, and disseminate best practices in data use and informatics to the CTSA community.

Next Generation Data Sharing

This core aims to develop an open-science ethos and unite CTSA community data sharing with broader global efforts.

Tools & Cloud Infrastructure

This core aims to establish a common tool and cloud computing architecture to provide CTSA hubs with an affordable, easy to use, and scalable deployment paradigm.

11

Current CTSA Projects

98

Institutions working with CD2H

220

Faculty working with CD2H

NCATS Translational Science Spectrum

Public Health In this stage, researchers study health outcomes at the population level to determine the effects of diseases and identify efforts to prevent, diagnose, and treat them. Clinical Implementation This stage involves the adoption of interventions that have been demonstrated to be useful in a research environment into routine clinical care for the general population. Clinical Research Research in this stage includes studies to better understand a disease in humans and relate this knowledge to findings in cell or animal models; testing and refinement of new technologies in people; testing of interventions for safety and effectiveness in those with or without disease; and outcomes of health services research. Preclinical Research Preclinical research connects the basic science of disease with human medicine. During this stage, scientists develop model interventions to further understand the basis of a disease or disorder and find ways to treat it. Basic Research Basic research involves scientific exploration that can reveal fundamental mechanisms of biology, disease, or behavior. Every stage of the translational research spectrum builds upon and informs basic research. Translational Science The field of investigation focused on understanding the scientific and operational principles underlying each step of the translational process. TS Spectrum The translational science spectrum represents each stage of research along the path from the biological basis of health and disease to interventions that improve the health of individuals and the public. "> "> "> "> "> "> "> "> Learn more